Gene Information
Gene NameVWC2
OrganismHomo sapiens (Human)
Gene Length325
Protein NamesBrorin (Brain-specific chordin-like protein) (von Willebrand factor C domain-containing protein 2)
Target NameNA
Target TypeNA
Gene Age950 ( ENSG00000188730 )
Evolutionary StageEumetazoa
AlphaFoldDBQ2TAL6
Gene CardVWC2
Uniprot IDQ2TAL6
PfamPF00093
In ASDno
Allosteric Predictionno (-0.859013041)
Ortholog in AnimalsAlpaca_ VWC2 ( ortholog_one2one )
Dog_ VWC2 ( ortholog_one2one )
GuineaPig_ VWC2 ( ortholog_one2one )
Macaque_ VWC2 ( ortholog_one2one )
Mouse_ Vwc2 ( ortholog_one2one )
Pig_ VWC2 ( ortholog_one2one )
Rat_ Vwc2 ( ortholog_one2one )
OhnologsNA
ParalogsCHRDL1, MUC5B, KCP, CHRDL2, CHRD, VWF, VWCE, OTOGL, MUC6, MUC5AC, OTOG, ZAN, BMPER, TECTA, FCGBP, CRIM1, MUC2, MUC19, VWC2L
Tissueheart, ovary
Tissue SpecificityNA
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP rs769604 
Subcellular location [CC]Secreted, extracellular space, extracellular matrix, basement membrane {ECO:0000250}. Synapse {ECO:0000250}.
Mouse PG classificationNA
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