| Gene Information | |
|---|---|
| Gene Name | VTI1B |
| Organism | Homo sapiens (Human) |
| Gene Length | 232 |
| Protein Names | Vesicle transport through interaction with t-SNAREs homolog 1B (Vesicle transport v-SNARE protein Vti1-like 1) (Vti1-rp1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 950 ( ENSG00000100568 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q9UEU0 |
| Gene Card | VTI1B |
| Uniprot ID | Q9UEU0 |
| Pfam | PF05008 |
| In ASD | no |
| Allosteric Prediction | no (-0.4369535) |
| Ortholog in Animals | Alpaca_ VTI1B ( ortholog_one2one ) Dog_ RDH11 ( ortholog_one2one ) GuineaPig_ VTI1B ( ortholog_one2one ) Macaque_ VTI1B ( ortholog_one2one ) Mouse_ Vti1b ( ortholog_one2one ) Pig_ VTI1B ( ortholog_one2one ) Rat_ Vti1b ( ortholog_one2one ) Rabbit_ VTI1B ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | GOSR2, VTI1A |
| Tissue | NA |
| Tissue Specificity | Expressed in all tissues examined. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2V8S (X-ray 2.22A ) |
| DBSNP | NA |
| Subcellular location [CC] | Early endosome membrane {ECO:0000269|PubMed:18033301}; Single-pass type IV membrane protein {ECO:0000255}. Late endosome membrane {ECO:0000269|PubMed:18033301, ECO:0000269|PubMed:23217709}; Single-pass type IV membrane protein {ECO:0000269|PubMed:23217709}. Lysosome membrane {ECO:0000269|PubMed:18033301, ECO:0000269|PubMed:23217709}. Cytoplasmic granule {ECO:0000269|PubMed:23217709}. Recycling endosome membrane {ECO:0000269|PubMed:18033301}; Single-pass type IV membrane protein {ECO:0000255}. |
| Mouse PG classification | NA |
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