| Gene Information | |
|---|---|
| Gene Name | VSTM3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 244 |
| Protein Names | T-cell immunoreceptor with Ig and ITIM domains (V-set and immunoglobulin domain-containing protein 9) (V-set and transmembrane domain-containing protein 3) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q495A1 |
| Gene Card | TIGIT |
| Uniprot ID | Q495A1 |
| Pfam | PF07686 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Expressed at low levels on peripheral memory and regulatory CD4+ T-cells and NK cells and is up-regulated following activation of these cells (at protein level). {ECO:0000269|PubMed:19011627}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.066667(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 3Q0H (X-ray 1.70A ) 3RQ3 (X-ray 2.70A ) 3UCR (X-ray 2.63A ) 3UDW (X-ray 2.90A ) 5V52 (X-ray 3.10A ) 7VYT (X-ray 1.53A ) |
| DBSNP | rs13098836 |
| Subcellular location [CC] | Cell membrane {ECO:0000269|PubMed:19011627}; Single-pass type I membrane protein {ECO:0000269|PubMed:19011627}. |
| Mouse PG classification | NA |
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