| Gene Information | |
|---|---|
| Gene Name | VSIG4 |
| Organism | Homo sapiens (Human) |
| Gene Length | 399 |
| Protein Names | V-set and immunoglobulin domain-containing protein 4 (Protein Z39Ig) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 886 ( ENSG00000155659 ) |
| Evolutionary Stage | Mammalia |
| AlphaFoldDB | Q9Y279 |
| Gene Card | VSIG4 |
| Uniprot ID | Q9Y279 |
| Pfam | PF07686 |
| In ASD | no |
| Allosteric Prediction | no (-0.479209414) |
| Ortholog in Animals | Alpaca_ VSIG4 ( ortholog_one2one ) Dog_ VSIG4 ( ortholog_one2one ) Macaque_ VSIG4 ( ortholog_one2one ) Mouse_ Vsig4 ( ortholog_one2one ) Pig_ VSIG4 ( ortholog_one2one ) Rat_ Vsig4 ( ortholog_one2one ) Rabbit_ VSIG4 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | bone.marrow, dura.mater |
| Tissue Specificity | Abundantly expressed in several fetal tissues. In adult tissues, highest expression in lung and placenta. Expressed in resting macrophages. {ECO:0000269|PubMed:11004523, ECO:0000269|PubMed:17016562}. |
| Pharmacological Animal Models | 0.000730(Chimpanzee);0.001000(Mouse);0.001000(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2ICC (X-ray 1.20A ) 2ICE (X-ray 3.10A ) 2ICF (X-ray 4.10A ) 5IMK (X-ray 1.23A ) 5IML (X-ray 1.80A ) |
| DBSNP | rs34581041 rs34222730 rs17315645 rs35553694 |
| Subcellular location [CC] | Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}. |
| Mouse PG classification | NA |
| click here to return to the previous page | |