| Gene Information | |
|---|---|
| Gene Name | SLC7A10 |
| Organism | Homo sapiens (Human) |
| Gene Length | 523 |
| Protein Names | Asc-type amino acid transporter 1 (Asc-1) (Solute carrier family 7 member 10) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | >4290 ( ENSG00000130876 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | Q9NS82 |
| Gene Card | SLC7A10 |
| Uniprot ID | Q9NS82 |
| Pfam | PF13520 |
| In ASD | no |
| Allosteric Prediction | no (-0.603694344) |
| Ortholog in Animals | Alpaca_ SLC7A10 ( ortholog_one2one ) Dog_ SLC7A10 ( ortholog_one2one ) GuineaPig_ SLC7A10 ( ortholog_one2one ) Macaque_ SLC7A10 ( ortholog_one2one ) Mouse_ Slc7a10 ( ortholog_one2one ) Pig_ SLC7A10 ( ortholog_one2one ) Rat_ Slc7a10 ( ortholog_one2one ) Rabbit_ SLC7A10 ( ortholog_one2one ) |
| Ohnologs | SLC7A8, SLC7A6, SLC7A5, SLC7A7 |
| Paralogs | SLC7A6, SLC7A9, SLC7A8, SLC7A11, SLC7A13, SLC7A14, SLC7A7, SLC7A3, SLC7A2, SLC7A4, SLC7A1, SLC7A5 |
| Tissue | adipose.tissue, caudate.nucleus, greater.omentum, nucleus.accumbens, putamen, subcutaneous.adipose.tissue |
| Tissue Specificity | Expressed in brain, heart, kidney, liver, lung, pancreas, placenta, and skeletal muscle. {ECO:0000269|PubMed:10863037}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs79717007 rs34663170 |
| Subcellular location [CC] | Cell membrane {ECO:0000250|UniProtKB:P63115}; Multi-pass membrane protein {ECO:0000255}. Note=Colocalizes with OLIG2 in astrocytic processes. Localizes to the plasma membrane in mature adipocytes and to intracellular structures in preadipocytes. {ECO:0000250|UniProtKB:P63115}. |
| Mouse PG classification | NA |
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