| Gene Information | |
|---|---|
| Gene Name | SLC5A12 |
| Organism | Homo sapiens (Human) |
| Gene Length | 618 |
| Protein Names | Sodium-coupled monocarboxylate transporter 2 (Electroneutral sodium monocarboxylate cotransporter) (Low-affinity sodium-lactate cotransporter) (Solute carrier family 5 member 12) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 950 ( ENSG00000148942 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | Q1EHB4 |
| Gene Card | SLC5A12 |
| Uniprot ID | Q1EHB4 |
| Pfam | PF00474 |
| In ASD | no |
| Allosteric Prediction | no (-0.809560511) |
| Ortholog in Animals | Alpaca_ SLC5A12 ( ortholog_one2one ) Dog_ SLC5A12 ( ortholog_one2one ) GuineaPig_ SLC5A12 ( ortholog_one2one ) Macaque_ SLC5A12 ( ortholog_one2one ) Mouse_ Slc5a12 ( ortholog_one2one ) Pig_ SLC5A12 ( ortholog_one2one ) Rat_ Slc5a12 ( ortholog_one2one ) Rabbit_ SLC5A12 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | SLC5A11, SLC5A5, SLC5A8, SLC5A1, SLC5A6, SLC5A9, SLC5A3, SLC5A10, SLC5A4, SLC5A2, SLC5A7 |
| Tissue | kidney, small.intestine |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs12278761 |
| Subcellular location [CC] | Apical cell membrane {ECO:0000269|PubMed:17692818}; Multi-pass membrane protein {ECO:0000269|PubMed:17692818}. Note=Detected at the brush border membrane of the kidney. Colocalizes with viementin in Mueller cells (By similarity). {ECO:0000250}. |
| Mouse PG classification | NA |
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