| Gene Information | |
|---|---|
| Gene Name | VPREB1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 145 |
| Protein Names | Immunoglobulin iota chain (CD179 antigen-like family member A) (Protein VPreB1) (V(pre)B protein) (VpreB protein) (CD antigen CD179a) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 382 ( ENSG00000169575 ) |
| Evolutionary Stage | Mammalia |
| AlphaFoldDB | P12018 |
| Gene Card | VPREB1 |
| Uniprot ID | P12018 |
| Pfam | PF07686 |
| In ASD | no |
| Allosteric Prediction | no (-1.237435608) |
| Ortholog in Animals | Alpaca_ VPREB1 ( ortholog_one2one ) Dog_ VPREB1 ( ortholog_one2one ) GuineaPig_ VPREB1 ( ortholog_one2one ) Macaque_ VPREB1 ( ortholog_one2one ) Mouse_ Vpreb2 ( ortholog_one2many ) Mouse_ Vpreb1 ( ortholog_one2many ) Pig_ VPREB1 ( ortholog_one2one ) Rat_ Vpreb1 ( ortholog_one2many ) Rat_ Vpreb2 ( ortholog_one2many ) |
| Ohnologs | NA |
| Paralogs | IGLV7-46, IGLV7-43, TRDV3, IGKV4-1, TRAV9-2, TRAV9-1, IGKV1D-33, IGKV1-33, TRAV18, TRDV2, TRDV1, IGLV9-49, IGLV4-69, IGLV4-60, IGLV4-3, IGKV3-20, IGKV3D-20, IGKV3D-11, IGKV3-11, IGKV3D-7, IGKV3-15, IGKV3D-15, IGKV3-7, IGKV3OR2-268, TRAV40, IGKV1-27, IGKV6D-41, IGKV6D-21, IGKV6-21, IGKV2-30, IGKV2D-30, IGLV8-61, IGLV3-22, IGLV3-27, IGLV3-10, IGLV3-25, IGLV3-16, IGLV3-9, IGLV3-19, IGLV3-32, IGLV3-1, IGKV5-2, IGKV1-5, IGKV1-17, IGKV1-6, IGKV1-39, IGKV1D-39, IGKV1D-13, IGKV1-16, IGKV1D-17, IGKV1D-16, IGKV1D-12, IGKV1-12, IGKV1-8, IGKV1D-8, IGKV1D-42, IGKV1-9, IGKV1D-43, IGKV1-37, IGKV1D-37, IGLV3-21, IGLV3-12, IGKV1OR2-108, IGLV5-52, IGLV5-45, IGLV5-48, IGLV5-37, IGLV6-57, IGLV11-55, VPREB3, IGLV2-14, IGLV2-23, IGLV2-8, IGLV2-18, IGLV2-11, IGLV2-33, IGLV10-54, IGLV1-40, IGLV1-51, IGLV1-50, IGLV1-44, IGLV1-47, IGLV1-36, IGKV2D-24, IGKV2-24, TRAV14DV4, TRAV19, IGKV2D-40, IGKV2-40, IGKV2D-28, IGKV2-28, IGKV2D-26, IGKV2D-29 |
| Tissue | bone.marrow |
| Tissue Specificity | Only expressed by pre-B-cells. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2H32 (X-ray 2.70A ) 2H3N (X-ray 2.30A ) 3BJ9 (X-ray 2.00A ) |
| DBSNP | rs1320 rs11089979 rs5995720 |
| Subcellular location [CC] | Endoplasmic reticulum {ECO:0000250|UniProtKB:P13372}. |
| Mouse PG classification | NA |
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