Gene Information
Gene NameSPOPL
OrganismHomo sapiens (Human)
Gene Length392
Protein NamesSpeckle-type POZ protein-like (HIB homolog 2) (Roadkill homolog 2)
Target NameNA
Target TypeNA
Gene Age987 ( ENSG00000144228 )
Evolutionary StageEukaryota
AlphaFoldDBQ6IQ16
Gene CardSPOPL
Uniprot IDQ6IQ16
PfamPF00651; PF00917
In ASDno
Allosteric Predictionno (-1.209197667)
Ortholog in AnimalsAlpaca_ SPOPL ( ortholog_one2one )
Dog_ SPOPL ( ortholog_one2one )
GuineaPig_ SPOPL ( ortholog_one2one )
Macaque_ SPOPL ( ortholog_one2one )
Mouse_ Spopl ( ortholog_one2one )
Pig_ SPOPL ( ortholog_one2one )
Rat_ Spopl ( ortholog_one2one )
Rabbit_ SPOPL ( ortholog_one2one )
OhnologsSPOP
ParalogsBTBD9, ABTB2, BTBD1, KBTBD4, ABTB1, KLHL11, BTBD6, BTBD2, BTBD3, ABTB3, SPOP
TissueNA
Tissue SpecificityNA
Pharmacological Animal ModelsNULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.025(Rabbit)
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP rs36099753 
Subcellular location [CC]Nucleus {ECO:0000250}.
Mouse PG classificationNA
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