| Gene Information | |
|---|---|
| Gene Name | VOPP1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 172 |
| Protein Names | Vesicular, overexpressed in cancer, prosurvival protein 1 (EGFR-coamplified and overexpressed protein) (ECop) (Glioblastoma-amplified secreted protein) (Putative NF-kappa-B-activating protein 055N) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000154978 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q96AW1 |
| Gene Card | VOPP1 |
| Uniprot ID | Q96AW1 |
| Pfam | NA |
| In ASD | no |
| Allosteric Prediction | no (-1.498272462) |
| Ortholog in Animals | Alpaca_ VOPP1 ( ortholog_one2one ) Dog_ VOPP1 ( ortholog_one2one ) GuineaPig_ VOPP1 ( ortholog_one2one ) Macaque_ VOPP1 ( ortholog_one2one ) Mouse_ Vopp1 ( ortholog_one2one ) Pig_ VOPP1 ( ortholog_one2one ) Rat_ Vopp1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Widely expressed with highest levels in thymus and ovary. {ECO:0000269|PubMed:11916499}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasmic vesicle membrane {ECO:0000269|PubMed:20571887}; Single-pass type I membrane protein {ECO:0000269|PubMed:20571887}. Note=When overexpressed, localizes in the nucleus and perinuclear regions. |
| Mouse PG classification | NA |
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