Gene Information
Gene NameVMD2
OrganismHomo sapiens (Human)
Gene Length585
Protein NamesBestrophin-1 (TU15B) (Vitelliform macular dystrophy protein 2)
Target NameNA
Target TypeNA
Gene AgeNA
Evolutionary StageNA
AlphaFoldDBO76090
Gene CardBEST1
Uniprot IDO76090
PfamPF01062
In ASDno
Allosteric PredictionNA
Ortholog in AnimalsNA
OhnologsNA
ParalogsNA
TissueNA
Tissue SpecificityPredominantly expressed in the basolateral membrane of the retinal pigment epithelium.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 8D1I  (EM  1.82A  8D1J  (EM  2.05A  8D1K  (EM  2.28A  8D1L  (EM  2.12A  8D1M  (EM  3.11A  8D1O  (EM  2.44A 
DBSNP rs28940275  rs281865204  rs281865205  rs28940276  rs281865206  rs281865207  rs281865208  rs281865209  rs281865210  rs281865211  rs281865212  rs281865213  rs281865215  rs281865214  rs281865216  rs281865217  rs281865218  rs121918288  rs28940278  rs281865529  rs1591280714  rs281865221  rs281865530  rs28940274  rs121918289  rs281865223  rs281865224  rs281865225  rs281865224  rs28940273  rs281865226  rs281865227  rs281865228  rs281865229  rs281865230  rs281865232  rs281865231  rs281865273  rs1445469923  rs1805142  rs281865233  rs281865234  rs281865235  rs267606678  rs121918284  rs1800995  rs1417478879  rs200277476  rs199529046  rs765998048  rs267606680  rs74653691  rs281865237  rs281865275  rs281865238  rs281865239  rs281865238  rs281865240  rs281865241  rs281865242  rs281865243  rs267606677  rs28941469  rs267606676  rs281865244  rs281865245  rs281865245  rs121918291  rs281865246  rs121918290  rs281865247  rs137853905  rs28940570  rs281865276  rs281865248  rs281865250  rs281865251  rs281865253  rs281865254  rs281865255  rs1805143  rs1805143  rs281865257  rs28941468  rs1805144  rs281865258  rs281865261  rs281865259  rs281865263  rs281865262  rs281865263  rs281865264  rs281865265  rs281865267  rs281865266  rs281865268  rs281865269  rs281865270  rs281865271  rs281865277  rs121918287  rs368387447  rs17854138  rs200582915  rs147192139  rs281865283  rs148060787  rs1800010 
Subcellular location [CC]Cell membrane {ECO:0000269|PubMed:19853238, ECO:0000269|PubMed:26200502};
Multi-pass membrane protein {ECO:0000269|PubMed:19853238}. Basolateral cell membrane {ECO:0000269|PubMed:19853238, ECO:0000269|PubMed:26200502}.
Mouse PG classificationNA
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