| Gene Information | |
|---|---|
| Gene Name | IGHG3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 377 |
| Protein Names | Immunoglobulin heavy constant gamma 3 (HDC) (Heavy chain disease protein) (Ig gamma-3 chain C region) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 18 ( ENSG00000211897 ) |
| Evolutionary Stage | NA |
| AlphaFoldDB | P01860 |
| Gene Card | IGHG3 |
| Uniprot ID | P01860 |
| Pfam | PF07654 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | TRDC, IGHV4OR15-8, IGHV4-4, IGHV4-61, IGHV4-59, IGHV4-39, IGHV4-31, IGHV4-28, IGHV4-34, IGHV6-1, IGHV2-5, IGHV2OR16-5, IGHV2-26, IGHV2-70D, IGHV2-70, IGKC, IGHV5-51, IGHV5-10-1, IGHV1-69-2, IGHV1-24, IGHV1-3, IGHV1-58, IGHV1-45, IGHV1-18, IGHV1-69, IGHV1-69D, IGHV1-2, IGHV1OR15-1, IGHV1-46, IGHV1OR15-9, IGHV1OR21-1, IGHV3OR16-9, IGHV3OR16-8, IGHV3OR16-17, IGHV3-35, IGHV3-16, IGLL1, IGLC7, IGLC3, IGLC2, IGLC1, IGLL5, IGHV7-81, IGHV7-4-1, IGHE, IGHM, IGHV3-13, IGHV3OR16-10, IGHV3-48, IGHV3-21, IGHV3-11, IGHV3-43, IGHV3-20, IGHV3-74, IGHV3OR16-13, IGHV3-73, IGHV3-72, IGHV3OR15-7, IGHV3-15, IGHV3-49, IGHV3-30, IGHV3-33, IGHV3-7, IGHV8-51-1, IGHV3-64D, IGHV3-64, IGHV3-23, IGHV3-66, IGHV3-53, IGHV3-38, IGHV3OR16-12, IGHA1, IGHA2, IGHD, IGHG2, IGHG4, IGHG1 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 4WWI (X-ray 2.31A ) 4ZNC (X-ray 2.28A ) 5M3V (X-ray 1.97A ) 5W38 (X-ray 1.80A ) 6D58 (X-ray 2.39A ) 6G1E (X-ray 1.88A ) |
| DBSNP | NA |
| Subcellular location [CC] | Secreted {ECO:0000303|PubMed:20176268, ECO:0000303|PubMed:22158414}. Cell membrane {ECO:0000303|PubMed:20176268, ECO:0000303|PubMed:22158414}. |
| Mouse PG classification | NA |
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