| Gene Information | |
|---|---|
| Gene Name | OTOG |
| Organism | Homo sapiens (Human) |
| Gene Length | 2925 |
| Protein Names | Otogelin |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 950 ( ENSG00000188162 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | NA |
| Gene Card | OTOG |
| Uniprot ID | Q6ZRI0 |
| Pfam | PF05270; PF08742; PF01826; PF00094 |
| In ASD | no |
| Allosteric Prediction | no (-0.665656628) |
| Ortholog in Animals | Alpaca_ OTOG ( ortholog_one2one ) Dog_ OTOG ( ortholog_one2one ) GuineaPig_ OTOG ( ortholog_one2one ) Macaque_ OTOG ( ortholog_one2one ) Mouse_ Otog ( ortholog_one2one ) Pig_ OTOG ( ortholog_one2one ) Rat_ Otog ( ortholog_one2one ) Rabbit_ OTOG ( ortholog_one2one ) |
| Ohnologs | VWF |
| Paralogs | CHRDL1, MUC5B, KCP, CHRDL2, CHRD, VWF, VWCE, OTOGL, MUC6, MUC5AC, ZAN, BMPER, TECTA, FCGBP, CRIM1, MUC2, MUC19, VWC2L, VWC2 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs7130190 rs61611064 rs7112749 rs7106548 rs2355466 rs11024333 rs56359117 rs7936324 rs7936354 rs4491195 rs1256306888 rs1003490 rs7111528 rs11024341 rs397514607 rs12422210 rs11024357 |
| Subcellular location [CC] | Apical cell membrane {ECO:0000250|UniProtKB:O55225}; Peripheral membrane protein {ECO:0000250|UniProtKB:O55225}; Extracellular side {ECO:0000250|UniProtKB:O55225}. Secreted, extracellular space {ECO:0000250|UniProtKB:O55225}. Note=Found in fiber-like structures during the maturation process of the tectorial membrane. {ECO:0000250|UniProtKB:O55225}. |
| Mouse PG classification | NA |
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