| Gene Information | |
|---|---|
| Gene Name | FEZF1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 475 |
| Protein Names | Fez family zinc finger protein 1 (Zinc finger protein 312B) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000128610 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | A0PJY2 |
| Gene Card | FEZF1 |
| Uniprot ID | A0PJY2 |
| Pfam | PF00096 |
| In ASD | no |
| Allosteric Prediction | no (-1.128482201) |
| Ortholog in Animals | Alpaca_ FEZF1 ( ortholog_one2one ) GuineaPig_ FEZF1 ( ortholog_one2one ) Macaque_ FEZF1 ( ortholog_one2one ) Mouse_ Fezf1 ( ortholog_one2one ) Pig_ FEZF1 ( ortholog_one2one ) Rat_ Fezf1 ( ortholog_one2one ) Rabbit_ FEZF1 ( ortholog_one2one ) |
| Ohnologs | FEZF2 |
| Paralogs | PRDM12, ZNF280A, ZBTB33, ZBTB21, ZNF280C, NACC2, ZNF580, ZBTB26, NACC1, ZNF683, ZBTB7B, GFI1, PRDM13, ZNF280B, ZBTB6, ZBTB14, GFI1B, BCL6, ZBTB49, BCL6B, ZBTB3, ZNF581, FEZF2, ZNF280D, ZBTB46, ZNF524, ZBTB12, ZBTB25 |
| Tissue | NA |
| Tissue Specificity | Expressed in brain. Little or no expression in other tissues. Overexpressed specifically in gastric cancers. A 2- to 20-fold increase is found in over 50% of gastric cancer tissues. {ECO:0000269|PubMed:19318583}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs587777739 |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:19318583}. |
| Mouse PG classification | LPG |
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