| Gene Information | |
|---|---|
| Gene Name | ZFAND1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 268 |
| Protein Names | AN1-type zinc finger protein 1 (Zinc finger AN1-type-containing protein 1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000104231 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q8TCF1 |
| Gene Card | ZFAND1 |
| Uniprot ID | Q8TCF1 |
| Pfam | PF01428 |
| In ASD | no |
| Allosteric Prediction | no (-1.693724761) |
| Ortholog in Animals | Alpaca_ ZFAND1 ( ortholog_one2one ) Dog_ ZFAND1 ( ortholog_one2one ) Macaque_ ZFAND1 ( ortholog_one2one ) Mouse_ Zfand1 ( ortholog_one2one ) Pig_ ZFAND1 ( ortholog_one2one ) Rat_ Zfand1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | ZFAND2A, ZFAND2B |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 7Y39 (X-ray 1.88A ) |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm, Stress granule {ECO:0000269|PubMed:29804830}. Note=Colocalizes with TIA1, G3BP1, VCP and 26S proteasome in cytoplasmic stress granules (SGs) in response to arsenite-induced stress treatment in a VCP-independent manner (PubMed:29804830). Not localized in SGs in response to other heat- oxidative- or osmotic-induced stress treatments. Colocalizes with VCP in cytoplasmic speckles (PubMed:29804830). {ECO:0000269|PubMed:29804830}. |
| Mouse PG classification | NA |
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