| Gene Information | |
|---|---|
| Gene Name | VEGFC |
| Organism | Homo sapiens (Human) |
| Gene Length | 419 |
| Protein Names | Vascular endothelial growth factor C (VEGF-C) (Flt4 ligand) (Flt4-L) (Vascular endothelial growth factor-related protein) (VRP) |
| Target Name | vascular endothelial growth factor c |
| Target Type | Clinical trial target |
| Gene Age | 645 ( ENSG00000150630 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | P49767 |
| Gene Card | VEGFC |
| Uniprot ID | P49767 |
| Pfam | PF03128; PF00341 |
| In ASD | no |
| Allosteric Prediction | yes (0.624018434) |
| Ortholog in Animals | Alpaca_ VEGFC ( ortholog_one2one ) Dog_ VEGFC ( ortholog_one2one ) GuineaPig_ VEGFC ( ortholog_one2one ) Macaque_ VEGFC ( ortholog_one2one ) Mouse_ Vegfc ( ortholog_one2one ) Pig_ VEGFC ( ortholog_one2one ) Rat_ Vegfc ( ortholog_one2one ) Rabbit_ VEGFC ( ortholog_one2one ) |
| Ohnologs | VEGFA, VEGFD |
| Paralogs | VEGFD, PGF, VEGFA, VEGFB |
| Tissue | NA |
| Tissue Specificity | Spleen, lymph node, thymus, appendix, bone marrow, heart, placenta, ovary, skeletal muscle, prostate, testis, colon and small intestine and fetal liver, lung and kidney, but not in peripheral blood lymphocyte. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.010990(Rat);0.133333(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2X1W (X-ray 2.70A ) 2X1X (X-ray 3.10A ) 4BSK (X-ray 4.20A ) 6TJT (X-ray 1.31A ) |
| DBSNP | NA |
| Subcellular location [CC] | Secreted. |
| Mouse PG classification | HPG |
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