| Gene Information | |
|---|---|
| Gene Name | VEGFB |
| Organism | Homo sapiens (Human) |
| Gene Length | 207 |
| Protein Names | Vascular endothelial growth factor B (VEGF-B) (VEGF-related factor) (VRF) |
| Target Name | vascular endothelial growth factor b |
| Target Type | Successful target |
| Gene Age | 244 ( ENSG00000173511 ) |
| Evolutionary Stage | Mammalia |
| AlphaFoldDB | P49765 |
| Gene Card | VEGFB |
| Uniprot ID | P49765 |
| Pfam | PF00341 |
| In ASD | no |
| Allosteric Prediction | yes (0.29414702) |
| Ortholog in Animals | Alpaca_ VEGFB ( ortholog_one2one ) GuineaPig_ VEGFB ( ortholog_one2one ) Macaque_ VEGFB ( ortholog_one2one ) Mouse_ Vegfb ( ortholog_one2one ) Pig_ VEGFB ( ortholog_one2one ) Rat_ Vegfb ( ortholog_one2one ) |
| Ohnologs | PGF |
| Paralogs | VEGFD, VEGFC, PGF, VEGFA |
| Tissue | NA |
| Tissue Specificity | Expressed in all tissues except liver. Highest levels found in heart, skeletal muscle and pancreas. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2C7W (X-ray 2.48A ) 2VWE (X-ray 3.40A ) 2XAC (X-ray 2.71A ) 6TKK (X-ray 1.06A ) |
| DBSNP | NA |
| Subcellular location [CC] | Secreted. Note=Secreted but remains associated to cells or to the extracellular matrix unless released by heparin. |
| Mouse PG classification | NA |
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