| Gene Information | |
|---|---|
| Gene Name | VDAC3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 283 |
| Protein Names | Voltage-dependent anion-selective channel protein 3 (VDAC-3) (hVDAC3) (Outer mitochondrial membrane protein porin 3) |
| Target Name | voltage-dependent anion-selective channel 3 |
| Target Type | Clinical trial target |
| Gene Age | 1488 ( ENSG00000078668 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q9Y277 |
| Gene Card | VDAC3 |
| Uniprot ID | Q9Y277 |
| Pfam | PF01459 |
| In ASD | no |
| Allosteric Prediction | yes (0.229037922) |
| Ortholog in Animals | Alpaca_ VDAC3 ( ortholog_one2one ) Dog_ VDAC3 ( ortholog_one2many ) GuineaPig_ VDAC3 ( ortholog_one2one ) Macaque_ VDAC3 ( ortholog_one2one ) Mouse_ Vdac3 ( ortholog_one2one ) Pig_ VDAC3 ( ortholog_one2one ) Rabbit_ VDAC3 ( ortholog_one2one ) |
| Ohnologs | VDAC2P5, VDAC1 |
| Paralogs | VDAC1, VDAC2 |
| Tissue | NA |
| Tissue Specificity | Expressed in erythrocytes (at protein level) (PubMed:27641616). Widely expressed. Highest in testis (PubMed:9781040). {ECO:0000269|PubMed:27641616, ECO:0000269|PubMed:9781040}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Mitochondrion outer membrane {ECO:0000250|UniProtKB:P21796}. Membrane {ECO:0000269|PubMed:27641616}. Note=May localize to non-mitochondrial membranes. {ECO:0000269|PubMed:27641616}. |
| Mouse PG classification | NA |
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