| Gene Information | |
|---|---|
| Gene Name | VDAC2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 294 |
| Protein Names | Voltage-dependent anion-selective channel protein 2 (VDAC-2) (hVDAC2) (Outer mitochondrial membrane protein porin 2) |
| Target Name | voltage-dependent anion-selective channel protein 2 |
| Target Type | NA |
| Gene Age | 1488 ( ENSG00000165637 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | P45880 |
| Gene Card | VDAC2 |
| Uniprot ID | P45880 |
| Pfam | PF01459 |
| In ASD | no |
| Allosteric Prediction | yes (0.608611373) |
| Ortholog in Animals | Dog_ VDAC2 ( ortholog_one2one ) GuineaPig_ VDAC2 ( ortholog_one2one ) Macaque_ VDAC2 ( ortholog_one2one ) Mouse_ Vdac2 ( ortholog_one2one ) Pig_ VDAC2 ( ortholog_one2one ) Rat_ Vdac2 ( ortholog_one2many ) Rat_ AABR07051831.1 ( ortholog_one2many ) Rabbit_ VDAC2 ( ortholog_one2one ) |
| Ohnologs | VDAC1 |
| Paralogs | VDAC1, VDAC3 |
| Tissue | NA |
| Tissue Specificity | Expressed in erythrocytes (at protein level) (PubMed:27641616). Expressed in all tissues examined (PubMed:8420959). {ECO:0000269|PubMed:27641616, ECO:0000269|PubMed:8420959}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Mitochondrion outer membrane {ECO:0000269|PubMed:31015432, ECO:0000269|PubMed:7539795}. Membrane {ECO:0000269|PubMed:27641616}. Note=May localize to non-mitochondrial membranes. {ECO:0000269|PubMed:27641616}. |
| Mouse PG classification | NA |
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