| Gene Information | |
|---|---|
| Gene Name | VCPIP1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 1222 |
| Protein Names | Deubiquitinating protein VCPIP1 (EC 3.4.19.12) (Valosin-containing protein p97/p47 complex-interacting protein 1) (Valosin-containing protein p97/p47 complex-interacting protein p135) (VCP/p47 complex-interacting 135-kDa protein) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000175073 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q96JH7 |
| Gene Card | VCPIP1 |
| Uniprot ID | Q96JH7 |
| Pfam | PF02338; PF19437 |
| In ASD | no |
| Allosteric Prediction | no (-1.032363289) |
| Ortholog in Animals | Alpaca_ VCPIP1 ( ortholog_one2one ) Dog_ VCPIP1 ( ortholog_one2one ) GuineaPig_ VCPIP1 ( ortholog_one2one ) Macaque_ VCPIP1 ( ortholog_one2one ) Mouse_ Vcpip1 ( ortholog_one2one ) Pig_ VCPIP1 ( ortholog_one2one ) Rat_ Vcpip1 ( ortholog_one2one ) Rabbit_ VCPIP1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001657(Rat);0.026667(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:32649882}. Cytoplasm {ECO:0000269|PubMed:32649882}. Endoplasmic reticulum {ECO:0000250|UniProtKB:Q8CF97}. Golgi apparatus, Golgi stack {ECO:0000250|UniProtKB:Q8CF97}. Note=Associated with Golgi stacks and endoplasmic reticulum (By similarity). Displays cytoplasmic to nuclear translocation in response to DNA-protein cross-links (DPCs)-inducing agents (PubMed:32649882). {ECO:0000250|UniProtKB:Q8CF97, ECO:0000269|PubMed:32649882}. |
| Mouse PG classification | NA |
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