| Gene Information | |
|---|---|
| Gene Name | MYLK3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 819 |
| Protein Names | Myosin light chain kinase 3 (EC 2.7.11.18) (Cardiac-MyBP-C-associated Ca/CaM kinase) (Cardiac-MLCK) |
| Target Name | myosin light chain kinase 3 |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000140795 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | Q32MK0 |
| Gene Card | MYLK3 |
| Uniprot ID | Q32MK0 |
| Pfam | PF00069 |
| In ASD | no |
| Allosteric Prediction | yes (0.157674498) |
| Ortholog in Animals | Alpaca_ MYLK3 ( ortholog_one2one ) Dog_ MYLK3 ( ortholog_one2one ) GuineaPig_ MYLK3 ( ortholog_one2one ) Mouse_ Mylk3 ( ortholog_one2one ) Pig_ MYLK3 ( ortholog_one2one ) Rat_ Mylk3 ( ortholog_one2one ) Rabbit_ MYLK3 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | DCLK3, PHKG1, MYLK4, CAMKK1, CAMKK2, DCLK2, PSKH1, PNCK, CAMK1D, CAMKV, CAMK2B, CAMK1, STK11, STK33, PHKG2, DCLK1, PSKH2, CAMK2G, MYLK2, CAMK2D, CAMK2A, CAMK1G |
| Tissue | heart, atrium, left.ventricle |
| Tissue Specificity | Restricted to heart. {ECO:0000269|PubMed:17885681}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs9923813 rs28407821 rs141602742 |
| Subcellular location [CC] | Cytoplasm {ECO:0000250}. |
| Mouse PG classification | NA |
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