| Gene Information | |
|---|---|
| Gene Name | VATB |
| Organism | Homo sapiens (Human) |
| Gene Length | 513 |
| Protein Names | V-type proton ATPase subunit B, kidney isoform (V-ATPase subunit B 1) (Endomembrane proton pump 58 kDa subunit) (Vacuolar proton pump subunit B 1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | P15313 |
| Gene Card | ATP6V1B1 |
| Uniprot ID | P15313 |
| Pfam | PF00006; PF02874 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Kidney; localizes to early distal nephron, encompassing thick ascending limbs and distal convoluted tubules (at protein level) (PubMed:29993276, PubMed:16769747). Expressed in the cochlea and endolymphatic sac (PubMed:9916796). {ECO:0000269|PubMed:16769747, ECO:0000269|PubMed:29993276, ECO:0000269|PubMed:9916796}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.007735(Rat);0.308122(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs17720303 rs121964879 rs121964880 rs1343871627 rs727505222 rs782500780 rs114234874 rs1161604514 rs1553420413 rs781838938 rs142905621 |
| Subcellular location [CC] | Apical cell membrane {ECO:0000269|PubMed:16769747, ECO:0000269|PubMed:29993276}. Basolateral cell membrane {ECO:0000250|UniProtKB:Q91YH6}. |
| Mouse PG classification | NA |
| click here to return to the previous page | |