| Gene Information | |
|---|---|
| Gene Name | VAT1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 393 |
| Protein Names | Synaptic vesicle membrane protein VAT-1 homolog (EC 1.-.-.-) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | >4290 ( ENSG00000108828 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q99536 |
| Gene Card | VAT1 |
| Uniprot ID | Q99536 |
| Pfam | PF08240 |
| In ASD | no |
| Allosteric Prediction | yes (0.082227761) |
| Ortholog in Animals | Alpaca_ VAT1 ( ortholog_one2one ) Dog_ VAT1 ( ortholog_one2one ) GuineaPig_ VAT1 ( ortholog_one2one ) Macaque_ VAT1 ( ortholog_one2one ) Mouse_ Vat1 ( ortholog_one2one ) Pig_ VAT1 ( ortholog_one2one ) Rat_ Vat1 ( ortholog_one2one ) |
| Ohnologs | VAT1L |
| Paralogs | MECR, CRYZ, RTN4IP1, PTGR2, TP53I3, CRYZL1, PTGR3, ADH6, ADH4, SORD, ADH1B, ADH1A, ADH1C, VAT1L, PTGR1, ADH5, ADH7 |
| Tissue | NA |
| Tissue Specificity | Expressed in brain. Also expressed in glioblastoma cells. {ECO:0000269|PubMed:19508442}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
|
| PDB | 6K9Y (X-ray 2.20A ) 6LHR (X-ray 2.62A ) 6LII (X-ray 2.30A ) |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm. Mitochondrion outer membrane; Peripheral membrane protein. Note=The majority is localized in the cytoplasm and a small amount is associated with mitochondria. {ECO:0000250}. |
| Mouse PG classification | NA |
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