| Gene Information | |
|---|---|
| Gene Name | DUSP3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 185 |
| Protein Names | Dual specificity protein phosphatase 3 (EC 3.1.3.16) (EC 3.1.3.48) (Dual specificity protein phosphatase VHR) (Vaccinia H1-related phosphatase) (VHR) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 382 ( ENSG00000108861 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | P51452 |
| Gene Card | DUSP3 |
| Uniprot ID | P51452 |
| Pfam | PF00782 |
| In ASD | yes |
| Allosteric Prediction | yes (0.411596762) |
| Ortholog in Animals | Alpaca_ DUSP3 ( ortholog_one2one ) Dog_ DUSP3 ( ortholog_one2one ) Pig_ DUSP3 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | DUSP6, DUSP4, DUSP12, DUSP10, STYXL2, SSH3, DUSP19, DUSP1, KASH5, SSH1, DUSP29, DUSP16, DUSP21, DUSP2, DUSP8, DUSP13, EPM2A, DUSP7, DUSP26, STYX, SSH2, PTPMT1, DUSP22, DUSP18, DUSP15, DUSP14, DUSP28, STYXL1, DUSP5, DUSP9 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1J4X (X-ray 2.75A ) 1VHR (X-ray 2.10A ) 3F81 (X-ray 1.90A ) |
| DBSNP | NA |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:10224087}. |
| Mouse PG classification | NA |
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