| Gene Information | |
|---|---|
| Gene Name | VARS2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 1063 |
| Protein Names | Valine--tRNA ligase, mitochondrial (EC 6.1.1.9) (Valyl-tRNA synthetase) (ValRS) (Valyl-tRNA synthetase-like) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000137411 ) 3 ( ENSG00000206476 ) 3 ( ENSG00000223494 ) 3 ( ENSG00000230985 ) 3 ( ENSG00000234032 ) 3 ( ENSG00000236178 ) |
| Evolutionary Stage | Cellular_organisms |
| AlphaFoldDB | Q5ST30 |
| Gene Card | VARS2 |
| Uniprot ID | Q5ST30 |
| Pfam | PF08264; PF00133 |
| In ASD | no |
| Allosteric Prediction | no (-0.709707288) |
| Ortholog in Animals | Alpaca_ VARS2 ( ortholog_one2one ) Dog_ VARS2 ( ortholog_one2one ) GuineaPig_ VARS2 ( ortholog_one2one ) Macaque_ VARS2 ( ortholog_one2one ) Mouse_ Vars2 ( ortholog_one2one ) Pig_ VARS2 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | VARS1, MARS2, MARS1, LARS2, IARS1, IARS2, LARS1 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs6926224 rs6926723 rs587777585 rs587777583 rs2249464 rs587777584 rs2074506 rs55865499 rs9394021 rs2252863 rs4678 |
| Subcellular location [CC] | Mitochondrion {ECO:0000305}. |
| Mouse PG classification | NA |
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