Gene Information
Gene NameCAMK2D
OrganismHomo sapiens (Human)
Gene Length499
Protein NamesCalcium/calmodulin-dependent protein kinase type II subunit delta (CaM kinase II subunit delta) (CaMK-II subunit delta) (EC 2.7.11.17)
Target Namecalcium/calmodulin-dependent protein kinase type ii subunit delta
Target TypeNA
Gene Age78 ( ENSG00000145349 )
Evolutionary StageEuk+Bac
AlphaFoldDBQ13557
Gene CardCAMK2D
Uniprot IDQ13557
PfamPF08332; PF00069
In ASDno
Allosteric Predictionyes (1.390482743)
Ortholog in AnimalsDog_ CAMK2D ( ortholog_one2one )
Pig_ CAMK2D ( ortholog_one2one )
Rabbit_ CAMK2D ( ortholog_one2one )
OhnologsCAMK2B, CAMK2A, CAMK2G
ParalogsDCLK3, PHKG1, MYLK4, CAMKK1, CAMKK2, DCLK2, PSKH1, PNCK, CAMK1D, CAMKV, CAMK2B, CAMK1, STK11, STK33, PHKG2, DCLK1, PSKH2, CAMK2G, MYLK2, MYLK3, CAMK1G, CAMK2A
TissueNA
Tissue SpecificityExpressed in cardiac muscle and skeletal muscle. Isoform Delta 3, isoform Delta 2, isoform Delta 8 and isoform Delta 9 are expressed in cardiac muscle. Isoform Delta 11 is expressed in skeletal muscle. {ECO:0000269|PubMed:10189359, ECO:0000269|PubMed:16690701}.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 2VN9  (X-ray  2.30A  2W2C  (X-ray  2.70A  2WEL  (X-ray  1.90A  3GP2  (X-ray  1.46A  5VLO  (X-ray  2.05A  6AYW  (X-ray  2.05A 
DBSNP rs35367671  rs1053668  rs35765784 
Subcellular location [CC]Cell membrane, sarcolemma {ECO:0000305};
Peripheral membrane protein {ECO:0000305};
Cytoplasmic side {ECO:0000305}. Sarcoplasmic reticulum membrane {ECO:0000305};
Peripheral membrane protein {ECO:0000305};
Cytoplasmic side {ECO:0000305}.
Mouse PG classificationNA
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