| Gene Information | |
|---|---|
| Gene Name | VAMP4 |
| Organism | Homo sapiens (Human) |
| Gene Length | 141 |
| Protein Names | Vesicle-associated membrane protein 4 (VAMP-4) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1488 ( ENSG00000117533 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | O75379 |
| Gene Card | VAMP4 |
| Uniprot ID | O75379 |
| Pfam | PF00957 |
| In ASD | no |
| Allosteric Prediction | no (-0.760321952) |
| Ortholog in Animals | Alpaca_ VAMP4 ( ortholog_one2one ) Dog_ VAMP4 ( ortholog_one2one ) Macaque_ VAMP4 ( ortholog_one2one ) Mouse_ Vamp4 ( ortholog_one2one ) Pig_ VAMP4 ( ortholog_one2one ) Rat_ Vamp4 ( ortholog_one2one ) Rabbit_ VAMP4 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | VAMP8, VAMP2, SEC22A, VAMP7, VAMP3, VAMP1, SEC22C, VAMP5, SEC22B, YKT6 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.014286(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Golgi apparatus, trans-Golgi network membrane {ECO:0000305}; Single-pass type IV membrane protein {ECO:0000305}. Note=Associated with trans Golgi network (TGN) and newly formed immature secretory granules (ISG). Not found on the mature secretory organelles. |
| Mouse PG classification | NA |
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