| Gene Information | |
|---|---|
| Gene Name | UXT |
| Organism | Homo sapiens (Human) |
| Gene Length | 157 |
| Protein Names | Protein UXT (Androgen receptor trapped clone 27 protein) (ART-27) (Ubiquitously expressed transcript protein) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000126756 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q9UBK9 |
| Gene Card | UXT |
| Uniprot ID | Q9UBK9 |
| Pfam | PF02996 |
| In ASD | no |
| Allosteric Prediction | no (-0.89056956) |
| Ortholog in Animals | Alpaca_ UXT ( ortholog_one2one ) Dog_ UXT ( ortholog_one2one ) GuineaPig_ UXT ( ortholog_one2one ) Macaque_ UXT ( ortholog_one2one ) Mouse_ Uxt ( ortholog_one2one ) Pig_ UXT ( ortholog_one2one ) Rat_ Uxt ( ortholog_one2one ) Rabbit_ UXT ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Ubiquitous (PubMed:10087202, PubMed:11854421, PubMed:17635584, PubMed:11827465). Expressed in prostate epithelial cells (PubMed:21730289). Expressed in mammary epithelial cells (PubMed:28106301). Highest levels in the heart, skeletal muscle, pancreas, kidney, liver, adrenal gland, peripheral blood leukocytes, lymph node, prostate, and thyroid and the lowest levels in bladder and uterus (PubMed:11854421, PubMed:17635584, PubMed:11827465). Overexpressed in a number of tumor tissues (PubMed:11854421, PubMed:16221885, PubMed:28106301). {ECO:0000269|PubMed:10087202, ECO:0000269|PubMed:11827465, ECO:0000269|PubMed:11854421, ECO:0000269|PubMed:16221885, ECO:0000269|PubMed:17635584, ECO:0000269|PubMed:21730289, ECO:0000269|PubMed:28106301}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001390(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
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| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | [Isoform 1]: Cytoplasm {ECO:0000269|PubMed:21307340}.; Cytoplasm {ECO:0000269|PubMed:21307340, ECO:0000305|PubMed:28106301}. Nucleus {ECO:0000269|PubMed:11854421, ECO:0000269|PubMed:17620405, ECO:0000269|PubMed:21307340, ECO:0000305|PubMed:28106301}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269|PubMed:16221885}. Cytoplasm, cytoskeleton, spindle pole {ECO:0000269|PubMed:16221885}. Note=Predominantly localizes to the nucleus (PubMed:16221885). Localizes to spindle pole during mitosis (PubMed:16221885). {ECO:0000269|PubMed:16221885, ECO:0000269|PubMed:21307340}. |
| Mouse PG classification | NA |
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