| Gene Information | |
|---|---|
| Gene Name | TENT5C |
| Organism | Homo sapiens (Human) |
| Gene Length | 391 |
| Protein Names | Terminal nucleotidyltransferase 5C (EC 2.7.7.19) (Non-canonical poly(A) polymerase FAM46C) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 810 ( ENSG00000183508 ) |
| Evolutionary Stage | Opisthokonta |
| AlphaFoldDB | Q5VWP2 |
| Gene Card | TENT5C |
| Uniprot ID | Q5VWP2 |
| Pfam | PF07984 |
| In ASD | no |
| Allosteric Prediction | no (-1.310302025) |
| Ortholog in Animals | Alpaca_ TENT5C ( ortholog_one2one ) Dog_ TENT5C ( ortholog_one2one ) GuineaPig_ TENT5C ( ortholog_one2one ) Macaque_ TENT5C ( ortholog_one2one ) Mouse_ Tent5c ( ortholog_one2one ) Pig_ TENT5C ( ortholog_one2one ) Rat_ Tent5c ( ortholog_one2one ) |
| Ohnologs | TENT5A, TENT5D, TENT5B |
| Paralogs | TENT5A, TENT5D, TENT5B |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.005990(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 6W36 (X-ray 2.85A ) 6W38 (X-ray 4.48A ) 6W3I (X-ray 3.80A ) 6W3J (X-ray 4.38A ) |
| DBSNP | rs1630312 |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:28931820}. Cytoplasm {ECO:0000269|PubMed:28931820}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269|PubMed:32433990}. Note=Recruited into the centrosome through its interaction with PLK4. {ECO:0000269|PubMed:32433990}. |
| Mouse PG classification | NA |
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