| Gene Information | |
|---|---|
| Gene Name | My014 |
| Organism | Homo sapiens (Human) |
| Gene Length | 541 |
| Protein Names | Sorting nexin-27 |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q96L92 |
| Gene Card | SNX27 |
| Uniprot ID | Q96L92 |
| Pfam | PF00595; PF00787; PF00788 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Widely expressed. Expressed in cells of hematopoietic origin (at protein level). {ECO:0000269|PubMed:17351151, ECO:0000269|PubMed:17577583, ECO:0000269|PubMed:21300787}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 4HAS (X-ray 1.74A ) 5ZN9 (X-ray 1.78A ) 6SAK (X-ray 2.00A ) 7CT1 (X-ray 1.95A ) 7E0B (X-ray 1.29A ) 7P72 (X-ray 2.15A ) 7PCB (X-ray 2.00A ) |
| DBSNP | rs11204871 |
| Subcellular location [CC] | Early endosome membrane; Peripheral membrane protein. Cytoplasm, cytosol. Note=Localizes to immunological synapse in T-cells. In T-cells, recruited from the cytosol to sorting endosomes by phosphoinositide-3-kinase products. |
| Mouse PG classification | NA |
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