| Gene Information | |
|---|---|
| Gene Name | MRAS |
| Organism | Homo sapiens (Human) |
| Gene Length | 208 |
| Protein Names | Ras-related protein M-Ras (EC 3.6.5.2) (Ras-related protein R-Ras3) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1488 ( ENSG00000158186 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | O14807 |
| Gene Card | MRAS |
| Uniprot ID | O14807 |
| Pfam | PF00071 |
| In ASD | no |
| Allosteric Prediction | yes (0.093945824) |
| Ortholog in Animals | Alpaca_ MRAS ( ortholog_one2one ) Dog_ MRAS ( ortholog_one2one ) GuineaPig_ MRAS ( ortholog_one2one ) Macaque_ MRAS ( ortholog_one2one ) Mouse_ Mras ( ortholog_one2one ) Pig_ MRAS ( ortholog_one2one ) Rat_ Mras ( ortholog_one2one ) Rabbit_ MRAS ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | RRAS, RHEB, KRAS, DIRAS1, RRAS2, RAP2B, HRAS, RERG, RASL12, RRAD, RIT1, DIRAS2, ERAS, NKIRAS1, RALB, RASD2, GEM, DIRAS3, RAP2A, RASD1, REM1, NKIRAS2, RALA, RAP1A, RASL11B, RAP1B, RASL10A, RASL11A, REM2, RERGL, RIT2, RHEBL1, NRAS, RAP2C, RASL10B |
| Tissue | NA |
| Tissue Specificity | Expression highly restricted to the brain and heart. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 7SD0 (EM 2.95A ) 7TVF (X-ray 2.17A ) 7TXH (X-ray 1.95A ) 7UPI (EM 2.89A ) |
| DBSNP | NA |
| Subcellular location [CC] | Cell membrane {ECO:0000305}; Lipid-anchor {ECO:0000305}; Cytoplasmic side {ECO:0000305}. |
| Mouse PG classification | NA |
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