| Gene Information | |
|---|---|
| Gene Name | UTP20 |
| Organism | Homo sapiens (Human) |
| Gene Length | 2785 |
| Protein Names | Small subunit processome component 20 homolog (Down-regulated in metastasis protein) (Novel nucleolar protein 73) (NNP73) (Protein Key-1A6) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | >4290 ( ENSG00000120800 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | NA |
| Gene Card | UTP20 |
| Uniprot ID | O75691 |
| Pfam | PF07539; PF20416 |
| In ASD | no |
| Allosteric Prediction | no (-1.15824105) |
| Ortholog in Animals | Alpaca_ UTP20 ( ortholog_one2one ) Dog_ UTP20 ( ortholog_one2one ) GuineaPig_ UTP20 ( ortholog_one2one ) Macaque_ UTP20 ( ortholog_one2one ) Mouse_ Utp20 ( ortholog_one2one ) Pig_ UTP20 ( ortholog_one2one ) Rat_ Utp20 ( ortholog_one2one ) Rabbit_ UTP20 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Expressed in appendix, brain, colon, fetal liver, heart, ovary, pancreas, placenta, prostate, skeletal muscle, small intestine, spleen, testis and thymus. {ECO:0000269|PubMed:9673349}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.453729(Rat);0.098531(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 7MQ8 (EM 3.60A ) 7MQ9 (EM 3.87A ) 7MQA (EM 2.70A ) |
| DBSNP | rs2290723 rs4764643 rs140657361 rs10082778 rs1061436 |
| Subcellular location [CC] | Nucleus, nucleolus {ECO:0000269|PubMed:11790298, ECO:0000269|PubMed:12429849, ECO:0000269|PubMed:16458307}. Note=Colocalizes with NCL in the nucleolus. |
| Mouse PG classification | NA |
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