| Gene Information | |
|---|---|
| Gene Name | UT2H |
| Organism | Homo sapiens (Human) |
| Gene Length | 551 |
| Protein Names | Solute carrier family 22 member 4 (Ergothioneine transporter) (ET transporter) (Organic cation/carnitine transporter 1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q9H015 |
| Gene Card | SLC22A4 |
| Uniprot ID | Q9H015 |
| Pfam | PF00083 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Widely expressed. Highly expressed in whole blood, bone marrow, trachea and fetal liver. Weakly expressed in kidney, skeletal muscle, prostate, lung, pancreas, placenta, heart, uterus, spleen and spinal cord. Highly expressed in intestinal cell types affected by Crohn disease, including epithelial cells. Expressed in CD68 macrophage and CD43 T-cells but not in CD20 B-cells. Predominantly expressed in CD14 cells in peripheral blood mononuclear cells. {ECO:0000269|PubMed:14608356, ECO:0000269|PubMed:15107849, ECO:0000269|PubMed:9426230}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs272893 rs4646201 rs1050152 |
| Subcellular location [CC] | Membrane; Multi-pass membrane protein. |
| Mouse PG classification | NA |
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