Gene Information
Gene NameSPOUT1
OrganismHomo sapiens (Human)
Gene Length376
Protein NamesPutative methyltransferase C9orf114 (EC 2.1.1.-) (Centromere protein 32) (CENP-32) (Kinetochore-associated protein) (SPOUT domain-containing methyltransferase 1)
Target NameNA
Target TypeNA
Gene Age>4290 ( ENSG00000198917 )
Evolutionary StageEuk_Archaea
AlphaFoldDBQ5T280
Gene CardSPOUT1
Uniprot IDQ5T280
PfamPF02598
In ASDno
Allosteric Predictionno (-1.474445566)
Ortholog in AnimalsAlpaca_ SPOUT1 ( ortholog_one2one )
Dog_ SPOUT1 ( ortholog_one2many )
GuineaPig_ SPOUT1 ( ortholog_one2one )
Mouse_ Spout1 ( ortholog_one2one )
Pig_ SPOUT1 ( ortholog_one2one )
Rat_ Spout1 ( ortholog_one2one )
OhnologsNA
ParalogsNA
TissueNA
Tissue SpecificityNA
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 4RG1  (X-ray  1.86A 
DBSNP rs34500948  rs6478854  rs2280843 
Subcellular location [CC]Cytoplasm, cytoskeleton, spindle {ECO:0000269|PubMed:25657325}. Chromosome, centromere, kinetochore {ECO:0000269|PubMed:20813266, ECO:0000269|PubMed:25657325}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269|PubMed:25657325}. Note=Associated with the outer kinetochore. {ECO:0000269|PubMed:20813266}.
Mouse PG classificationNA
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