| Gene Information | |
|---|---|
| Gene Name | USP53 |
| Organism | Homo sapiens (Human) |
| Gene Length | 1073 |
| Protein Names | Inactive ubiquitin carboxyl-terminal hydrolase 53 (Inactive ubiquitin-specific peptidase 53) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 544 ( ENSG00000145390 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q70EK8 |
| Gene Card | USP53 |
| Uniprot ID | Q70EK8 |
| Pfam | PF00443 |
| In ASD | no |
| Allosteric Prediction | no (-0.923337163) |
| Ortholog in Animals | Alpaca_ USP53 ( ortholog_one2one ) Dog_ USP53 ( ortholog_one2one ) Macaque_ USP53 ( ortholog_one2one ) Mouse_ Usp53 ( ortholog_one2one ) Pig_ USP53 ( ortholog_one2one ) Rat_ Usp53 ( ortholog_one2one ) Rabbit_ USP53 ( ortholog_one2one ) |
| Ohnologs | USP54 |
| Paralogs | USP54 |
| Tissue | NA |
| Tissue Specificity | Expressed predominantly in skeletal muscle and heart. {ECO:0000269|PubMed:14715245}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs3749591 |
| Subcellular location [CC] | Cell junction, tight junction {ECO:0000250|UniProtKB:P15975}. |
| Mouse PG classification | NA |
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