Gene Information
Gene NameUSP40
OrganismHomo sapiens (Human)
Gene Length1235
Protein NamesUbiquitin carboxyl-terminal hydrolase 40 (EC 3.4.19.12) (Deubiquitinating enzyme 40) (Ubiquitin thioesterase 40) (Ubiquitin-specific-processing protease 40)
Target NameNA
Target TypeNA
Gene Age1714 ( ENSG00000085982 )
Evolutionary StageEukaryota
AlphaFoldDBQ9NVE5
Gene CardUSP40
Uniprot IDQ9NVE5
PfamPF00443
In ASDno
Allosteric Predictionno (-0.705451298)
Ortholog in AnimalsAlpaca_ USP40 ( ortholog_one2one )
Dog_ USP40 ( ortholog_one2one )
GuineaPig_ USP40 ( ortholog_one2one )
Macaque_ USP40 ( ortholog_one2one )
Mouse_ Usp40 ( ortholog_one2one )
Pig_ USP40 ( ortholog_one2one )
Rat_ Usp40 ( ortholog_one2one )
Rabbit_ USP40 ( ortholog_one2one )
OhnologsNA
ParalogsUSP11, USP20, USP4, USP5, USP42, USP14, USP29, USP25, USP48, USP2, USP47, USP3, USP1, USP34, USP8, USP21, USP24, USP38, USP32, USP6, USP31, USP50, USP13, USP7, USP43, USP17L4, USP17L11, USP17L27, USP17L22, USP17L30, USP17L17, USP17L26, USP17L25, USP17L12, USP17L10, USP17L28, USP17L1, USP17L5, USP17L24, USP17L21, USP17L3, USP17L29, USP17L18, USP17L13, USP17L15, USP17L7, USP17L23, USP17L2, USP17L20, USP17L8, USP17L19, USP35, USP45, USP33, USP49, USP51, USP19, USP15, USP28, USP9X, USP9Y, USP27X, USP44, USP18, USP30, USP10, USP22, USP26, USP16, USP37, USP36
TissueNA
Tissue SpecificityBroadly expressed. {ECO:0000269|PubMed:14715245}.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP rs838543  rs34026756  rs1048603 
Subcellular location [CC]NA
Mouse PG classificationNA
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