| Gene Information | |
|---|---|
| Gene Name | PRKD3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 890 |
| Protein Names | Serine/threonine-protein kinase D3 (EC 2.7.11.13) (Protein kinase C nu type) (Protein kinase EPK2) (nPKC-nu) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000115825 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | O94806 |
| Gene Card | PRKD3 |
| Uniprot ID | O94806 |
| Pfam | PF00130; PF00169; PF00069 |
| In ASD | no |
| Allosteric Prediction | no (-0.13992091) |
| Ortholog in Animals | Alpaca_ PRKD3 ( ortholog_one2one ) Dog_ PRKD3 ( ortholog_one2one ) GuineaPig_ PRKD3 ( ortholog_one2one ) Macaque_ PRKD3 ( ortholog_one2one ) Mouse_ Prkd3 ( ortholog_one2one ) Pig_ PRKD3 ( ortholog_one2one ) Rat_ Prkd3 ( ortholog_one2one ) Rabbit_ PRKD3 ( ortholog_one2one ) |
| Ohnologs | PRKD2, PRKD1 |
| Paralogs | PRKD2, PRKD1 |
| Tissue | NA |
| Tissue Specificity | Ubiquitous. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2D9Z (NMR - ) |
| DBSNP | rs11896614 rs17852819 rs34280934 rs55912911 rs17856887 |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:18076381}. Membrane {ECO:0000269|PubMed:18076381}. Note=Translocation to the cell membrane is required for kinase activation. |
| Mouse PG classification | NA |
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