| Gene Information | |
|---|---|
| Gene Name | SLC18A3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 532 |
| Protein Names | Vesicular acetylcholine transporter (VAChT) (Solute carrier family 18 member 3) |
| Target Name | vesicular acetylcholine transporter |
| Target Type | Discontinued target |
| Gene Age | 810 ( ENSG00000187714 ) |
| Evolutionary Stage | Cellular_organisms |
| AlphaFoldDB | Q16572 |
| Gene Card | SLC18A3 |
| Uniprot ID | Q16572 |
| Pfam | PF07690 |
| In ASD | yes |
| Allosteric Prediction | yes (1.000402297) |
| Ortholog in Animals | Alpaca_ SLC18A3 ( ortholog_one2one ) Dog_ SLC18A3 ( ortholog_one2one ) GuineaPig_ SLC18A3 ( ortholog_one2one ) Macaque_ SLC18A3 ( ortholog_one2one ) Mouse_ Slc18a3 ( ortholog_one2one ) Pig_ SLC18A3 ( ortholog_one2one ) Rabbit_ SLC18A3 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | SLC18B1, SLC18A2, SLC18A1 |
| Tissue | NA |
| Tissue Specificity | Peripheral and central cholinergic nervous systems. {ECO:0000269|PubMed:8071310}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs8187732 rs8187733 rs8187734 rs1057517665 rs1057517666 rs8187730 |
| Subcellular location [CC] | Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane {ECO:0000250|UniProtKB:Q62666}; Multi-pass membrane protein {ECO:0000255}. |
| Mouse PG classification | NA |
| click here to return to the previous page | |