| Gene Information | |
|---|---|
| Gene Name | IGFBP4 |
| Organism | Homo sapiens (Human) |
| Gene Length | 258 |
| Protein Names | Insulin-like growth factor-binding protein 4 (IBP-4) (IGF-binding protein 4) (IGFBP-4) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 544 ( ENSG00000141753 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | P22692 |
| Gene Card | IGFBP4 |
| Uniprot ID | P22692 |
| Pfam | PF00219; PF00086 |
| In ASD | no |
| Allosteric Prediction | no (-0.088308633) |
| Ortholog in Animals | Alpaca_ IGFBP4 ( ortholog_one2one ) Dog_ IGFBP4 ( ortholog_one2one ) GuineaPig_ IGFBP4 ( ortholog_one2one ) Macaque_ IGFBP4 ( ortholog_one2one ) Mouse_ Igfbp4 ( ortholog_one2one ) Pig_ IGFBP4 ( ortholog_one2one ) Rat_ Igfbp4 ( ortholog_one2one ) Rabbit_ IGFBP4 ( ortholog_one2one ) |
| Ohnologs | IGFBP2, IGFBP5, IGFBP3, IGFBP1, IGFBP6 |
| Paralogs | IGFBP6, IGFBP3, IGFBP2, IGFBP1, IGFBP5 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.003490(Rat);0.133333(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1WQJ (X-ray 1.60A ) 2DSP (X-ray 2.50A ) 2DSQ (X-ray 2.80A ) 2DSR (X-ray 2.10A ) |
| DBSNP | rs599199 |
| Subcellular location [CC] | Secreted. |
| Mouse PG classification | NA |
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