| Gene Information | |
|---|---|
| Gene Name | PANK3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 370 |
| Protein Names | Pantothenate kinase 3 (hPanK3) (EC 2.7.1.33) (Pantothenic acid kinase 3) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000120137 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q9H999 |
| Gene Card | PANK3 |
| Uniprot ID | Q9H999 |
| Pfam | PF03630 |
| In ASD | yes |
| Allosteric Prediction | yes (0.390291331) |
| Ortholog in Animals | Alpaca_ PANK3 ( ortholog_one2one ) Dog_ PANK3 ( ortholog_one2one ) GuineaPig_ PANK3 ( ortholog_one2one ) Macaque_ PANK3 ( ortholog_one2one ) Mouse_ Pank3 ( ortholog_one2one ) Pig_ PANK3 ( ortholog_one2one ) Rat_ Pank3 ( ortholog_one2one ) Rabbit_ PANK3 ( ortholog_one2one ) |
| Ohnologs | PANK2, PANK1 |
| Paralogs | PANK2, PANK4, PANK1 |
| Tissue | NA |
| Tissue Specificity | Highly expressed in the liver. {ECO:0000269|PubMed:11479594}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2I7P (X-ray 2.05A ) 3MK6 (X-ray 1.98A ) 3SMS (X-ray 2.20A ) 5KPR (X-ray 1.83A ) 5KPT (X-ray 2.30A ) 5KPZ (X-ray 2.40A ) 5KQ8 (X-ray 2.00A ) 5KQD (X-ray 2.60A ) 6B3V (X-ray 1.60A ) 6PE6 (X-ray 1.60A ) 6X4J (X-ray 2.30A ) 6X4K (X-ray 2.10A ) 6X4L (X-ray 2.00A ) |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:23152917, ECO:0000305}. |
| Mouse PG classification | NA |
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