| Gene Information | |
|---|---|
| Gene Name | UROS |
| Organism | Homo sapiens (Human) |
| Gene Length | 265 |
| Protein Names | Uroporphyrinogen-III synthase (UROIIIS) (UROS) (EC 4.2.1.75) (Hydroxymethylbilane hydrolyase [cyclizing]) (Uroporphyrinogen-III cosynthase) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 680 ( ENSG00000188690 ) |
| Evolutionary Stage | Opisthokonta |
| AlphaFoldDB | P10746 |
| Gene Card | UROS |
| Uniprot ID | P10746 |
| Pfam | PF02602 |
| In ASD | no |
| Allosteric Prediction | no (-0.438003886) |
| Ortholog in Animals | Alpaca_ UROS ( ortholog_one2one ) Dog_ UROS ( ortholog_one2one ) GuineaPig_ UROS ( ortholog_one2one ) Macaque_ UROS ( ortholog_one2one ) Mouse_ Uros ( ortholog_one2one ) Pig_ UROS ( ortholog_one2one ) Rat_ Uros ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Ubiquitous. {ECO:0000269|PubMed:11112350}. |
| Pharmacological Animal Models | 0.000730(Chimpanzee);NULL(Mouse);NULL(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1JR2 (X-ray 1.84A ) |
| DBSNP | rs773301339 rs121908015 rs397515527 rs121908013 rs28941775 rs28941774 rs121908012 rs121908016 rs397515528 rs17153561 rs17173752 rs121908017 rs121908017 rs139388833 rs767029901 rs121908020 rs121908014 rs777433697 rs121908021 |
| Subcellular location [CC] | NA |
| Mouse PG classification | NA |
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