| Gene Information | |
|---|---|
| Gene Name | URGCP |
| Organism | Homo sapiens (Human) |
| Gene Length | 931 |
| Protein Names | Up-regulator of cell proliferation (HBV X protein up-regulated gene 4 protein) (HBxAg up-regulated gene 4 protein) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000106608 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q8TCY9 |
| Gene Card | URGCP |
| Uniprot ID | Q8TCY9 |
| Pfam | NA |
| In ASD | no |
| Allosteric Prediction | no (-1.339454908) |
| Ortholog in Animals | Alpaca_ URGCP ( ortholog_one2one ) Dog_ URGCP ( ortholog_one2one ) GuineaPig_ URGCP ( ortholog_one2one ) Macaque_ URGCP ( ortholog_one2one ) Mouse_ Urgcp ( ortholog_one2one ) Pig_ URGCP ( ortholog_one2one ) Rat_ Urgcp ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Strongly expressed in hepatitis B virus-infected liver and in HCC cells. Also highly expressed in well-differentiated gastric cancer tissues and various gastric cancer cell lines. {ECO:0000269|PubMed:12082552, ECO:0000269|PubMed:17217616}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs2232106 rs2232107 rs2232108 |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:12082552, ECO:0000269|PubMed:17217616}. Nucleus {ECO:0000269|PubMed:12082552, ECO:0000269|PubMed:17217616}. Note=In epithelial cells localized predominantly in the cytoplasm and occasionally in nuclei. |
| Mouse PG classification | NA |
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