| Gene Information | |
|---|---|
| Gene Name | UQCRC2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 453 |
| Protein Names | Cytochrome b-c1 complex subunit 2, mitochondrial (Complex III subunit 2) (Core protein II) (Ubiquinol-cytochrome-c reductase complex core protein 2) |
| Target Name | cytochrome b-c1 complex subunit 2, mitochondrial |
| Target Type | NA |
| Gene Age | >4290 ( ENSG00000140740 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | P22695 |
| Gene Card | UQCRC2 |
| Uniprot ID | P22695 |
| Pfam | PF00675; PF05193 |
| In ASD | no |
| Allosteric Prediction | yes (0.382034316) |
| Ortholog in Animals | Alpaca_ UQCRC2 ( ortholog_one2one ) Dog_ UQCRC2 ( ortholog_one2one ) GuineaPig_ UQCRC2 ( ortholog_one2one ) Mouse_ Uqcrc2 ( ortholog_one2one ) Pig_ UQCRC2 ( ortholog_one2one ) Rat_ Uqcrc2 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | PMPCA, UQCRC1, PITRM1, NRDC, PMPCB, IDE |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.642466(Rat);0.240267(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 5XTE (EM 3.40A ) 5XTH (EM 3.90A ) 5XTI (EM 17.40A ) |
| DBSNP | rs2228473 rs4850 rs374661051 rs11863893 |
| Subcellular location [CC] | Mitochondrion inner membrane {ECO:0000250|UniProtKB:P07257}; Peripheral membrane protein {ECO:0000250|UniProtKB:P07257}; Matrix side {ECO:0000250|UniProtKB:P07257}. |
| Mouse PG classification | NA |
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