| Gene Information | |
|---|---|
| Gene Name | UPRT |
| Organism | Homo sapiens (Human) |
| Gene Length | 309 |
| Protein Names | Uracil phosphoribosyltransferase homolog |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 950 ( ENSG00000094841 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q96BW1 |
| Gene Card | UPRT |
| Uniprot ID | Q96BW1 |
| Pfam | NA |
| In ASD | no |
| Allosteric Prediction | no (-0.24590943) |
| Ortholog in Animals | Alpaca_ UPRT ( ortholog_one2one ) Dog_ UPRT ( ortholog_one2one ) GuineaPig_ UPRT ( ortholog_one2one ) Macaque_ UPRT ( ortholog_one2one ) Mouse_ Uprt ( ortholog_one2one ) Pig_ UPRT ( ortholog_one2one ) Rat_ Uprt ( ortholog_one2one ) Rabbit_ UPRT ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | UCKL1, UCK1, UCK2 |
| Tissue | NA |
| Tissue Specificity | Highly expressed in leukocytes, liver, spleen and thymus, with lower expression in brain, lung and skeletal muscle. {ECO:0000269|PubMed:17384901}. |
| Pharmacological Animal Models | 0.014235(Chimpanzee);0.013613(Mouse);NULL(Rat);0.091667(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:17384901}. Nucleus {ECO:0000269|PubMed:17384901}. |
| Mouse PG classification | NA |
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