| Gene Information | |
|---|---|
| Gene Name | UPK2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 184 |
| Protein Names | Uroplakin-2 (UP2) (Uroplakin II) (UPII) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 454 ( ENSG00000110375 ) |
| Evolutionary Stage | Mammalia |
| AlphaFoldDB | O00526 |
| Gene Card | UPK2 |
| Uniprot ID | O00526 |
| Pfam | PF07353 |
| In ASD | no |
| Allosteric Prediction | no (-1.283951173) |
| Ortholog in Animals | Alpaca_ UPK2 ( ortholog_one2one ) Dog_ UPK2 ( ortholog_one2one ) GuineaPig_ UPK2 ( ortholog_one2one ) Macaque_ UPK2 ( ortholog_one2one ) Mouse_ Upk2 ( ortholog_one2one ) Pig_ UPK2 ( ortholog_one2one ) Rat_ Upk2 ( ortholog_one2one ) Rabbit_ UPK2 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | urinary.bladder |
| Tissue Specificity | Expressed in ureter. {ECO:0000269|PubMed:9846985}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs3886020 rs45530531 |
| Subcellular location [CC] | Cell membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}. Note=Heterodimer formation with UPK1A is a prerequisite to exit out of the endoplasmic reticulum (ER). {ECO:0000250}. |
| Mouse PG classification | NA |
| click here to return to the previous page | |