| Gene Information | |
|---|---|
| Gene Name | UPB1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 384 |
| Protein Names | Beta-ureidopropionase (EC 3.5.1.6) (BUP-1) (Beta-alanine synthase) (N-carbamoyl-beta-alanine amidohydrolase) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1488 ( ENSG00000100024 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q9UBR1 |
| Gene Card | UPB1 |
| Uniprot ID | Q9UBR1 |
| Pfam | PF00795 |
| In ASD | no |
| Allosteric Prediction | no (-0.012209015) |
| Ortholog in Animals | Alpaca_ UPB1 ( ortholog_one2one ) Dog_ UPB1 ( ortholog_one2one ) GuineaPig_ UPB1 ( ortholog_one2one ) Macaque_ UPB1 ( ortholog_one2one ) Mouse_ Upb1 ( ortholog_one2one ) Pig_ UPB1 ( ortholog_one2one ) Rat_ Upb1 ( ortholog_one2one ) Rabbit_ UPB1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NIT2, NIT1 |
| Tissue | liver, kidney |
| Tissue Specificity | Detected in liver (at protein level). {ECO:0000269|PubMed:22525402}. |
| Pharmacological Animal Models | 0.000730(Chimpanzee);NULL(Mouse);NULL(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 6FTQ (X-ray 2.08A ) |
| DBSNP | rs200688546 rs34035085 rs766196011 rs144135211 rs747454154 rs200034079 rs118163237 rs34110964 rs369879221 |
| Subcellular location [CC] | Cytoplasm. |
| Mouse PG classification | NA |
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