| Gene Information | |
|---|---|
| Gene Name | AK8 |
| Organism | Homo sapiens (Human) |
| Gene Length | 479 |
| Protein Names | Adenylate kinase 8 (AK 8) (EC 2.7.4.3) (EC 2.7.4.6) (ATP-AMP transphosphorylase 8) |
| Target Name | adenylate kinase 8 |
| Target Type | NA |
| Gene Age | 424 ( ENSG00000165695 ) |
| Evolutionary Stage | Opisthokonta |
| AlphaFoldDB | Q96MA6 |
| Gene Card | AK8 |
| Uniprot ID | Q96MA6 |
| Pfam | NA |
| In ASD | no |
| Allosteric Prediction | yes (0.003050878) |
| Ortholog in Animals | Alpaca_ AK8 ( ortholog_one2one ) Dog_ AK8 ( ortholog_one2one ) GuineaPig_ AK8 ( ortholog_one2one ) Macaque_ AK8 ( ortholog_one2one ) Mouse_ Ak8 ( ortholog_one2one ) Pig_ AK8 ( ortholog_one2one ) Rat_ Ak8 ( ortholog_one2one ) Rabbit_ AK8 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | CMPK1, AK5, AK1, AK7, AK3, AK9, AK2, AK4, AK4P3 |
| Tissue | testis, oviduct |
| Tissue Specificity | Expressed in respiratory cells (at protein level). {ECO:0000269|PubMed:33139725}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs2231400 rs17407084 |
| Subcellular location [CC] | Cytoplasm, cytosol {ECO:0000269|PubMed:21080915}. Cytoplasm, cytoskeleton, cilium axoneme {ECO:0000269|PubMed:33139725}. Note=Located in the proximal region of respiratory cilia. {ECO:0000269|PubMed:33139725}. |
| Mouse PG classification | NA |
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