| Gene Information | |
|---|---|
| Gene Name | UPA |
| Organism | Homo sapiens (Human) |
| Gene Length | 151 |
| Protein Names | Proline-rich acidic protein 1 (Epididymis tissue protein Li 178) (Uterine-specific proline-rich acidic protein) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q96NZ9 |
| Gene Card | PRAP1 |
| Uniprot ID | Q96NZ9 |
| Pfam | PF15314 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Highly expressed in the intestinal epithelial cells (at protein level) (PubMed:32629119). Abundantly expressed in the epithelial cells of the liver, kidney and cervix. Significantly down-regulated in hepatocellular carcinoma and right colon adenocarcinoma compared with the respective adjacent normal tissues. Expressed in epididymis (at protein level). {ECO:0000269|PubMed:14583459, ECO:0000269|PubMed:20736409, ECO:0000269|PubMed:24374861, ECO:0000269|PubMed:32629119}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs34780987 rs4369319 |
| Subcellular location [CC] | Secreted {ECO:0000269|PubMed:14583459}. Endoplasmic reticulum {ECO:0000250|UniProtKB:Q80XD8}. |
| Mouse PG classification | NA |
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