| Gene Information | |
|---|---|
| Gene Name | UNQ9356/PRO34128 |
| Organism | Homo sapiens (Human) |
| Gene Length | 394 |
| Protein Names | GDNF family receptor alpha-like |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q6UXV0 |
| Gene Card | GFRAL |
| Uniprot ID | Q6UXV0 |
| Pfam | PF02351 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Expressed in the brainstem, restricted to cells in the area postrema and the immediately adjacent region of the nucleus tractus solitarius (at protein level) (PubMed:28846097, PubMed:28846098). Detected at low levels in testis and adipose tissue (PubMed:28846097). {ECO:0000269|PubMed:28846097, ECO:0000269|PubMed:28846098}. |
| Pharmacological Animal Models | 0.000730(Chimpanzee);0.001000(Mouse);NULL(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 5VZ4 (X-ray 2.20A ) 6Q2J (EM 4.10A ) 6WMW (X-ray 2.91A ) |
| DBSNP | rs12199003 rs1224725337 rs9370418 |
| Subcellular location [CC] | Cell membrane {ECO:0000269|PubMed:28953886}; Single-pass membrane protein {ECO:0000269|PubMed:28953886}; Extracellular side {ECO:0000269|PubMed:28953886}. |
| Mouse PG classification | NA |
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