| Gene Information | |
|---|---|
| Gene Name | UNQ9339/PRO34011 |
| Organism | Homo sapiens (Human) |
| Gene Length | 551 |
| Protein Names | Gliomedin [Cleaved into: Gliomedin shedded ectodomain] |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q6ZMI3 |
| Gene Card | GLDN |
| Uniprot ID | Q6ZMI3 |
| Pfam | PF01391; PF02191 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Specifically expressed in spinal cord, brain, placenta and sciatic nerve. More abundant in peripheral than central nervous system. {ECO:0000269|PubMed:16039564}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 5YBY (X-ray 1.43A ) |
| DBSNP | rs779432560 rs17648128 rs17648128 rs35223886 rs764239923 |
| Subcellular location [CC] | Cell membrane {ECO:0000250|UniProtKB:Q80WL1, ECO:0000269|PubMed:27616481}; Single-pass type II membrane protein {ECO:0000250|UniProtKB:Q80WL1}. Cell projection, axon {ECO:0000250|UniProtKB:Q80WL1}. Note=Detected at the nodes of Ranvier. Detected at immature heminodes. {ECO:0000250|UniProtKB:Q80WL1}.; [Gliomedin shedded ectodomain]: Secreted {ECO:0000250|UniProtKB:Q80WL1}. Secreted, extracellular space, extracellular matrix {ECO:0000250|UniProtKB:Q80WL1}. Note=Proteolytic processing gives rise to a soluble extracellular domain that is secreted. The gliomedin shedded ectodomain localizes to the nodes of Ranvier. {ECO:0000250|UniProtKB:Q80WL1}. |
| Mouse PG classification | NA |
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