Gene Information
Gene NameGNRH1
OrganismHomo sapiens (Human)
Gene Length92
Protein NamesProgonadoliberin-1 (Progonadoliberin I) [Cleaved into: Gonadoliberin-1 (Gonadoliberin I) (Gonadorelin) (Gonadotropin-releasing hormone I) (GnRH-I) (Luliberin I) (Luteinizing hormone-releasing hormone I) (LH-RH I); GnRH-associated peptide 1 (GnRH-associated peptide I)]
Target Nameleutinizing-hormone-releasing hormone
Target TypeSuccessful target
Gene Age454 ( ENSG00000147437 )
Evolutionary StageVertebrata
AlphaFoldDBP01148
Gene CardGNRH1
Uniprot IDP01148
PfamPF00446
In ASDno
Allosteric Predictionno (-0.089973515)
Ortholog in AnimalsAlpaca_ GNRH1 ( ortholog_one2one )
Dog_ GNRH1 ( ortholog_one2one )
GuineaPig_ GNRH1 ( ortholog_one2one )
Macaque_ GNRH1 ( ortholog_one2one )
Mouse_ Gnrh1 ( ortholog_one2one )
Pig_ GNRH1 ( ortholog_one2one )
Rat_ Gnrh1 ( ortholog_one2one )
Rabbit_ GNRH1 ( ortholog_one2one )
OhnologsNA
ParalogsGNRH2
TissueNA
Tissue SpecificityNA
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 4D5M  (X-ray  0.85A 
DBSNP rs6185 
Subcellular location [CC]Secreted.
Mouse PG classificationNA
click here to return to the previous page