| Gene Information | |
|---|---|
| Gene Name | SEK |
| Organism | Homo sapiens (Human) |
| Gene Length | 986 |
| Protein Names | Ephrin type-A receptor 4 (EC 2.7.10.1) (EPH-like kinase 8) (EK8) (hEK8) (Tyrosine-protein kinase TYRO1) (Tyrosine-protein kinase receptor SEK) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | P54764 |
| Gene Card | EPHA4 |
| Uniprot ID | P54764 |
| Pfam | PF14575; PF01404; PF00041; PF07714; PF07647 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Ubiquitous. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.004323(Rat);0.02(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2LW8 (NMR - ) 2WO1 (X-ray 1.85A ) 2WO2 (X-ray 2.45A ) 2WO3 (X-ray 2.35A ) 3CKH (X-ray 2.80A ) 3GXU (X-ray 2.50A ) 4BK4 (X-ray 3.65A ) 4BK5 (X-ray 4.00A ) 4BKA (X-ray 5.30A ) 4BKF (X-ray 4.65A ) 4M4P (X-ray 2.08A ) 4M4R (X-ray 3.13A ) 4W4Z (X-ray 2.41A ) 4W50 (X-ray 2.42A ) 5JR2 (X-ray 1.75A ) 7OFV (X-ray 1.43A ) |
| DBSNP | rs35084379 rs756952113 rs868224085 rs35341687 |
| Subcellular location [CC] | Cell membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}. Cell projection, axon {ECO:0000250}. Cell projection, dendrite {ECO:0000250}. Postsynaptic density membrane {ECO:0000250}. Early endosome {ECO:0000250}. Cell junction, adherens junction {ECO:0000250|UniProtKB:Q03137}. Note=Clustered upon activation and targeted to early endosome. {ECO:0000250}. |
| Mouse PG classification | NA |
| click here to return to the previous page | |