| Gene Information | |
|---|---|
| Gene Name | BLVRA |
| Organism | Homo sapiens (Human) |
| Gene Length | 296 |
| Protein Names | Biliverdin reductase A (BVR A) (EC 1.3.1.24) (Biliverdin-IX alpha-reductase) |
| Target Name | biliverdin reductase a |
| Target Type | NA |
| Gene Age | 680 ( ENSG00000106605 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | P53004 |
| Gene Card | BLVRA |
| Uniprot ID | P53004 |
| Pfam | PF09166; PF01408 |
| In ASD | no |
| Allosteric Prediction | yes (0.406034409) |
| Ortholog in Animals | Alpaca_ BLVRA ( ortholog_one2one ) Dog_ BLVRA ( ortholog_one2one ) GuineaPig_ BLVRA ( ortholog_one2one ) Macaque_ BLVRA ( ortholog_one2one ) Mouse_ Blvra ( ortholog_one2one ) Pig_ BLVRA ( ortholog_one2one ) Rat_ Blvra ( ortholog_one2one ) Rabbit_ BLVRA ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | DHDH, GFOD2, GFOD1 |
| Tissue | NA |
| Tissue Specificity | Liver. {ECO:0000269|PubMed:7929092, ECO:0000269|PubMed:8424666}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2H63 (X-ray 2.70A ) |
| DBSNP | rs699512 rs17245918 rs1050916 |
| Subcellular location [CC] | Cytoplasm, cytosol {ECO:0000269|PubMed:7929092, ECO:0000269|PubMed:8424666}. |
| Mouse PG classification | NA |
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